Postdoc Research Associate in Peptide and Medicinal Chemistry

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    15 hours ago
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Opportunity to participate in an exciting NHMRC-funded research project relating to cancer research and synthetic chemistry
Located on the Camperdown Campus at the School of Chemistry
Full time, Level A fixed term, 2 years, offering a base salary of $96K – $106K p.a., plus leave loading and generous employer’s contribution to superannuation

About the opportunity

We are seeking to appoint a Postdoctoral Research Associate in Peptide and Medicinal Chemistry, who will be the primary synthetic chemist working with Dr Yu Heng Lau (School of Chemistry) on our NHMRC-funded project to develop new cancer therapeutics, synthesising and optimising peptide- and fragment-based chemical inhibitors of new protein targets that act at telomeres. In addition to inhibitor design and synthesis, you will have the opportunity to conduct in vitro biological testing of the synthesised compounds, while cell-based studies will be carried out with collaborator Prof. Hilda Pickett at the Children’s Medical Research Institute.

In this role, you will coordinate a team of PhD and MPhil students working on this research direction in the lab. You will have the opportunity to provide supervision for research students and be a good role model as a senior member of the research group, demonstrating professionalism in research ethics and integrity, day-to-day lab housekeeping and safe practices. Other responsibilities will consist of presenting research findings at conferences and preparing papers for publication in refereed journals. You will also gain experience in managing administrative tasks relating to project organisation and general lab operations within the group.

To learn more about the School of Chemistry, click here

To learn more about the research group of Dr Yu Heng Lau, you can visit and contact Yu Heng informally by email to learn more about the role.

About you

The University values courage and creativity; openness and engagement; inclusion and diversity; and respect and integrity. As such, we see the importance of recruiting talent aligned to these values and are looking for a Postdoctoral Research Associate in Peptide and Medicinal Chemistry who has:

a PhD (or near completion) in synthetic chemistry, chemical biology, biochemistry, or a closely related discipline
demonstrated ability to synthesise peptides and amino acids, including side-chain modifications and cyclisation
demonstrated knowledge of the field of peptide therapeutics, including the ability to critically assess published and unpublished data, and to formulate and successfully execute research plans
experience with operating HPLC and LCMS instruments
experience writing up results for publications in leading general interest chemistry/biology journals
experience presenting research at conferences
experience supervising junior researchers in the laboratory.

We will also consider organic chemists and medicinal chemists who have extensive experience in small molecule synthesis that can be applied to peptide synthesis.

Experience in conducting biological experiments (including biophysical assays, protein expression, cell culture) is desirable but not essential.

Please outline your relevant skills and experience in your cover letter and attach to your online application.


Your employment is conditional upon the completion of all role required pre-employment or background checks in terms satisfactory to the University. Similarly, your ongoing employment is conditional upon the satisfactory maintenance of all relevant clearances and background check requirements. If you do not meet these conditions, the University may take any necessary step, including the termination of your employment.

The University of Sydney is committed to diversity and social inclusion. Applications from people of culturally and linguistically diverse backgrounds; equity target groups including women, people with disabilities, people who identify as LGBTIQ; and people of Aboriginal and Torres Strait Islander descent, are encouraged.

© The University of Sydney

The University reserves the right not to proceed with any appointment.